Biorouter AI Agent Marketplace
One-click downloads for Biorouter extensions, community workflows, and reusable skills.
Download a .brxt bundle and drag it into Biorouter → Extensions → Add Extension. Biorouter installs the environment, configures the tool, and adds it to your session — no terminal needed.
More integrations
0 Community MCP adapters · v0.1.0Multimodal access to the UCSF Clinical Data Warehouse through natural language. One-call cohort building across diagnoses, medications, procedures, labs, radiology/imaging, immunizations, allergies, and vitals; clinical-notes/NLP search; read-only queries, schema discovery, and structured results. Requires UCSF network credentials (CAMPUS\username and password).
Natural language SQL on the UCSF OMOP de-identified clinical database. Read-only access to standardized EHR data under the OMOP Common Data Model. v0.2.0 adds built-in OMOP/SQL-Server context plus concept-search, lab-finder, and live schema tools so the agent reaches the right data faster and more reliably. Requires UCSF credentials.
Browser automation via Microsoft's @playwright/mcp. Navigate websites, extract data, fill forms, and run web research workflows using structured accessibility snapshots. No vision model required. Requires Node.js on the host.
Structure-aware access to the SPOKE biomedical knowledge graph (43M nodes): live schema introspection, entity/identifier resolution, node profiling, shortest-path finding, and guarded read-only Cypher across diseases, genes, proteins, drugs, and pathways. Includes a bundled spoke-knowledge-graph skill. Requires a SPOKEAGENT_PASSCODE (see credentials page).
Pre-indexed code knowledge graph. Ask "who calls X?", "what does Y call?", or "what breaks if I change Z?" across 23 languages including R, Julia, MATLAB, Perl. Vendored fork of CodeGraph on tree-sitter.
Create, read, and edit Word (.docx), Excel (.xlsx), and PowerPoint (.pptx) files from chat. Handles headings, tables, charts, and 150+ Excel functions with live formula evaluation. Built on the open-source OfficeCLI engine, so no Microsoft Office install is needed. Ships four bundled skills for the office suite, Word, Excel, and PowerPoint.
Read-only and confirmation-gated MCP access to Benchling projects, registry records, notebook entries, and assay metadata for scientific workflow review.
MCP access to DNAnexus project, file, app, workflow, and job metadata with guarded API calls for cloud bioinformatics runs.
MCP access to LatchBio workspace, workflow, file, and execution metadata with guarded API request helpers for reproducible computational biology workflows.
MCP access to LabArchives electronic lab notebook metadata and entries, with read-first notebook inspection and confirmation-gated API requests.
MCP access pattern for OMERO image repositories, project/dataset/image metadata, and web/API endpoint inspection for microscopy data review.
MCP access to Protocols.io public and authenticated protocol metadata for method discovery, citation, and reproducible protocol review.
MCP adapter for self-hosted or lab-hosted open-notebook systems, exposing guarded notebook entry search, retrieval, and provenance checks.
MCP helper for Modal compute projects, deployment planning, environment validation, and guarded command/API invocation for cloud scientific jobs.
MCP access to NCI Imaging Data Commons metadata endpoints for cancer imaging cohort discovery, DICOM collection review, and reproducible image-data queries.
MCP access pattern for PubMed, OpenAlex, Crossref, Semantic Scholar, and literature evidence workflows, with provenance-first search and guarded API calls.
MCP access to NCBI database discovery and Entrez-style workflows for PubMed, Gene, SRA, GEO, ClinVar, dbSNP, and sequence metadata review.
MCP access pattern for variant annotation resources such as ClinVar, VEP, MyVariant, and gnomAD, with normalization and clinical-evidence review safeguards.
Guarded MCP workflow runner for Nextflow, Snakemake, Cromwell/WDL, and CWL planning, validation, dry-run review, and confirmation-gated execution.
MCP helper for UCSF CHPC/SLURM job planning, account inspection, file transfer checks, and confirmation-gated HPC command execution.
MCP helper for RDKit, PubChem, ChEMBL, SMILES/InChI normalization, molecular descriptors, and guarded local cheminformatics command planning.
MCP access pattern for PDB, AlphaFold, UniProt, sequence-to-structure lookup, structure metadata review, and guarded local structure-tool planning.
MCP helper for scanpy/anndata-style single-cell workflows, h5ad metadata inspection, QC planning, clustering review, and guarded local command execution.
MCP adapter for Opentrons robot/run APIs, protocol metadata review, simulation planning, and guarded local Opentrons command execution.
MCP adapter for Ginkgo-style cloud lab project, run, sample, and protocol metadata with guarded authenticated API calls.
MCP adapter for LaminDB instance metadata, datasets, artifacts, collections, and guarded API/CLI planning for scientific data registries.
MCP adapter for CELLxGENE Census dataset and cell metadata discovery, with guarded API calls for single-cell atlas review.
MCP adapter for DepMap portal/API metadata, datasets, cell lines, genes, compounds, and cancer dependency evidence review.
MCP adapter for PrimeKG-style biomedical knowledge graph files and APIs, with guarded metadata lookup and graph-resource summaries.
MCP adapter for Zotero libraries, collections, items, tags, and citation metadata with read-first and mutation-gated API access.
MCP helper for MarkItDown-style document-to-Markdown conversion planning, status checks, and guarded local conversion commands.
MCP adapter for Adaptyv-style protein engineering design-build-test workflows, sequence libraries, experiment metadata, and result retrieval with guarded API calls.
MCP adapter for structured paper and full-text metadata search across scholarly APIs, section-aware evidence extraction, and provenance-first literature queries.
MCP adapter for scientific web and deep-research workflows, web search APIs, source fetching, and provenance capture beyond scholarly APIs.
MCP adapter for Tamarind Bio-style cloud protein, structure, docking, and design workflows with guarded API calls and result provenance.
MCP adapter for Rowan-style cloud molecular modeling: conformers, pKa, docking, analogue docking, cofolding, and medicinal chemistry calculation provenance.
Community workflows
All on GitHub →Query an OMOP-based EHR to identify a Type 2 Diabetes cohort, compute demographic summaries (gender, age, race, ethnicity), and auto-generate a shareable HTML report and interactive R Shiny dashboard. Runs at any OMOP-compatible institution without moving patient data.
version: 1.0.0 title: EHR Diabetes Demographics and Reporting Dashboard description: A workflow for querying an OMOP-based EHR to derive a disease cohort (e.g., T2D), summarize demographics, and produce sharable visual outputs. instructions: | Use an OMOP CDM clinical database to identify a patient cohort via diagnosis concepts. Join to person to obtain demographics and compute counts/percentages. Present results as an HTML report and optional R Shiny dashboard. activities: - Count disease cohort - Demographic breakdowns - Generate HTML report - Build Shiny dashboard extensions: []
.zip below, then in Biorouter open Skills → Add Skill and drag the .zip (or a single SKILL.md) into the drop zone. Biorouter unpacks the bundle into ~/.config/biorouter/skills/ and registers every SKILL.md inside. You can also unzip manually and copy the folder into ~/.config/biorouter/skills/. Skills appear under Biorouter → Skills automatically; auto-applied skills activate when relevant files are touched.
End-to-end literature research — search, read, and synthesize evidence with adversarial hypothesis verification and cited findings.
Publication-quality ggplot2 figures in R — font sizing, palettes, themes, and export settings tuned for journal submission.
scRNA-seq analysis — QC, clustering, annotation, trajectory, and integration with Scanpy, Seurat, and scVI.
End-to-end research: scopes the question, reviews real literature, generates hypotheses, plans and verifies the analysis, then writes a cited draft. Delegates biomedical data to BioSkills and the SPOKE/CDW/OMOP extensions. It never fabricates a citation or result.
Stage-gated empirical research workflow: design register, data audit, identification, estimation, robustness, replication, and reporting.
Audits whether RCT, observational, IV, RDD, DiD, synthetic-control, matching, DML, or survival designs support causal language.
Checks research packages for clean-run reproducibility, relative paths, environment capture, seeds, logs, and table/figure mapping.
Verifies that manuscript claims, numbers, citations, figures, and tables are grounded in traceable evidence.
Confirms citations are real, relevant, current enough for the claim, and temporally valid.
Known-answer benchmark patterns for testing whether empirical-analysis agents avoid common causal and reproducibility failures.
Plans and verifies DOCX/PDF/PPTX/XLSX/LaTeX/scientific figure artifacts with source-to-exhibit mapping.
Reviews data/code availability, reporting checklists, protocols, ethics/privacy notes, and open-science readiness.
Plans scalable scientific data workflows with Polars, Dask, Zarr, TileDB, Arrow/Parquet, HDF5, and dataset versioning.
Designs and critiques statistical, Bayesian, survival, hierarchical, power, and uncertainty-reporting workflows.
Plans scientific ML with leakage checks, transformers, graph neural networks, active learning, SHAP, and reproducibility gates.
Handles geospatial analysis with CRS checks, spatial joins, rasters/vectors, maps, and spatial statistics.
Plans biosignal and neural-recording analysis: ECG/EDA/PPG, spike sorting, Neuropixels metadata, and peri-event QC.
Routes quantum and scientific simulation work across Qiskit, Cirq, PennyLane, QuTiP, and validation checks.
Guides computational materials workflows with structures, crystals, compositions, phase diagrams, and dataset provenance.
Plans DICOM/pathology/PACS workflows with tiling, metadata, QC, cohort provenance, and privacy-safe reporting.
Builds, cleans, verifies, and deduplicates Zotero/BibTeX/RIS/CSL citation libraries.
Plans Opentrons/cloud-lab workflows with plate maps, protocol simulation, sample metadata, and execution gates.
Plans applied econometrics in Python, R, or Stata: panel data, IV, DiD, RDD, clustering, and replication tables.
Runs systematic-review workflows: PICO, search strings, screening logs, PRISMA flow, extraction, risk of bias, and synthesis.
Anti-slop frontend design for landing pages, dashboards, lab tools, and paper companion sites. Reads the brief, picks a real design direction, and ships interfaces that don't look templated.
Plans discrete-event simulation, multi-objective optimization, sensitivity analysis, scheduling, and what-if modeling.
Routes astronomy, physics, units, coordinate systems, spectra, numerical experiments, and physical-science workflows.
Guides COBRApy/FBA metabolic modeling with GPR rules, media constraints, knockouts, objectives, and provenance.
Plans ADMET, virtual-screening, molecular-property, scaffold-split, leakage, and assay-provenance benchmark checks.
Reviews clinical decision support, treatment plans, and reports for evidence grounding, safety scope, and no-PHI handling.
Plans schematics, posters, slides, figure panels, infographics, visual abstracts, and source-to-visual traceability.
Structures research grants, specific aims, milestones, reviewer-risk responses, and funder-fit checks.
Reviews scientific software, device, and lab processes against quality, validation, traceability, and design-control gates.
Plans GPU-bound training/inference, batching, profiling, memory pressure, mixed precision, and reproducible compute.
Evaluates papers, scholars, venues, impact claims, reviewer fit, and publication positioning.
Plans qualitative coding, thematic analysis, codebooks, memoing, inter-rater checks, and audit trails.
Plans empirical finance/accounting workflows with event studies, abnormal returns, panel data, and table replication.
Plans Stata .do/.dta research workflows: audits, logs, tables, graph export, replication, and R&R updates.
Handles complex survey designs with strata, PSUs, replicate weights, domain analysis, calibration, and weighted inference.
Plans reliability, CFA/SEM, mediation/moderation, invariance, item analysis, and APA-style measurement reporting.
Plans dictionaries, topic models, embeddings, sentiment, supervised coding, LLM-label validation, and measurement-error checks.
Routes empirical econ/finance sources including WRDS, CRSP, Compustat, SEC/EDGAR, NBER, SSRN, and public datasets.
Plans journal targeting, referee reports, response letters, revise-and-resubmit execution, and appendix organization.
Routes game theory, equilibrium, DSGE/HANK, structural IO, calibration, simulation, and identification-proof workflows.
Plans CATE, causal forests, meta-learners, policy learning, conformal causal inference, fairness, and subgroup reporting.
Detects repeated workflows and drafts native Biorouter skills, hooks, checklist updates, or extension plans.
Runs evaluator-driven branch-and-prune exploration for improving research artifacts, prompts, analyses, and designs.
Finds and evaluates Hugging Face scientific models, datasets, Spaces, and papers with license and provenance checks.
Plans MD setup and trajectory analysis with OpenMM, GROMACS, AmberTools, MDAnalysis, MDTraj, and reproducibility checks.
Plans non-omics forecasting with classical models, ML, foundation models, backtesting, leakage checks, and uncertainty.
Audits BIDS neuroimaging datasets, derivatives, validation, metadata, and reproducible preprocessing readiness.
Plans clinical AI modeling workflows with EHR cohorts, validation, bias checks, calibration, safety, and no-PHI handling.
Plans CFD workflows with meshes, boundary conditions, turbulence models, solver validation, and convergence checks.
A pass/fail checklist for spotting AI writing patterns before generating prose, articles, or essays.
Applies ggplot2 best-practice style when writing R plotting code.
Applies tidyverse conventions and documentation standards when writing or reviewing R code.
Applies Python naming, typing, error handling, and project structure conventions when writing Python code.
End-to-end planning for the Ralph autonomous agent loop. Drafts a markdown PRD from a feature idea, then converts it to prd.json. Each story is sized for one hands-off iteration.
Engineering discipline skills: brainstorming, TDD, systematic debugging, parallel agents, plan writing, code review, git worktrees. Workflows tested on long-running engineering tasks.
SSH setup, SLURM job templates (CPU/GPU/H200), file transfer, module management, and common pitfalls for the UCSF CHPC cluster.
Multi-stage, confidence-scored review of a pull request or local diff. Drops low-confidence findings and posts a formatted PR comment via gh.
Simplifies recently-changed code for clarity and consistency while preserving exact behavior. Defers language style to the Python and R skills.
Three git workflows: a clean single commit; commit + push + open a PR; and cleanup of [gone] branches and their worktrees.
The canonical guide to authoring Biorouter skills: frontmatter, progressive disclosure, packaging, and testing.
Step-by-step guide for building a .brxt extension: manifest, MCP server, packaging, validation, and bundled skills.
Turns project guardrails (warn/block rules) into real Biorouter hooks in .biorouter/hooks.yaml. A block rule stops the action; a warn rule shows a notice. Requires allow_project_hooks: true.
Phased legacy-modernization workflow (preflight, assess, map, extract rules, brief, transform, harden, status) for COBOL, legacy Java/C++, and monoliths.
Generates self-contained single-file interactive HTML playgrounds for configuring something visually, then copying out a ready-to-use prompt.
Anthropic's anti-slop frontend guidance for distinctive, production-grade UIs. Complements the Taste skill above.
Multiple sequence alignment and pairwise alignment.
SAM/BAM/CRAM manipulation, sorting, indexing, dedup, and stats.
RNA isoform and splice-junction analysis from short- and long-read data.
Chromatin accessibility, peak calling, footprinting, and deep-learning ATAC.
Mendelian randomization, colocalization, fine-mapping, and TWAS.
Molecular structure handling, descriptors, and drug-discovery utilities.
Transcription-factor and histone-mark peak calling and differential binding.
Survival, mixed models, and clinical-trial statistical analysis.
ClinVar, OMIM, COSMIC, gnomAD, and phenotype DB queries.
Protein–RNA interaction mapping from iCLIP/eCLIP/PAR-CLIP data.
Cross-species synteny, orthology, and selection scans.
CNV detection, visualization, and segmentation.
Pooled screen counting, MAGeCK analysis, and hit prioritization.
Publication-quality plots: heatmaps, volcano, Manhattan, dimplots.
NCBI, UniProt, Ensembl, and biological database APIs.
RNA-seq DE testing with DESeq2, edgeR, and limma-voom.
Environmental DNA, ecological population genomics, and biodiversity.
Pathogen typing, outbreak phylogeography, and surveillance.
m6A and other RNA modification detection from sequencing.
Power analysis and sample-size calculation for omics studies.
Count normalization, gene ID mapping, and matrix QC.
FCS parsing, gating, and high-dimensional cytometry analysis.
TF–target network inference from expression and chromatin data.
Gene prediction, repeat masking, and functional annotation.
De novo assembly, polishing, and assembly QC.
CRISPR guide design, off-target prediction, and editing analysis.
BED/GTF arithmetic, overlap, and feature manipulation.
3D chromatin contacts, TAD calling, and loop detection.
Single-cell spatial proteomics from IMC and MIBI data.
MHC binding, neoantigen prediction, and HLA typing.
Cell-free DNA fragmentomics, tumor fraction, and methylation cfDNA.
ONT and PacBio basecalling, alignment, and structural-variant workflows.
Biomarker discovery, model training, and cross-validation pipelines.
Mass-spec metabolite identification, alignment, and quantification.
Shotgun microbial profiling, assembly, and binning.
Bisulfite alignment and differential methylation testing.
16S rRNA amplicon and microbiota community profiling.
Cross-modality fusion: MOFA, DIABLO, WNN, totalVI.
GO, KEGG, Reactome, and GSEA enrichment testing.
Haplotype phasing and genotype imputation with SHAPEIT and Beagle.
Tree construction with IQ-TREE, RAxML, BEAST, and ancestral state.
GWAS, population structure, LD, and selection scans.
PCR and qPCR primer generation with Primer3 and primerBLAST.
Mass-spec quantification and protein abundance pipelines.
Short-read mapping with BWA-MEM2, Bowtie2, STAR, HISAT2.
FastQC, fastp, trimming, and contamination screening.
Reproducible HTML, Quarto, and R Markdown reports.
Restriction-enzyme mapping and digestion prediction.
Ribosome profiling and translation-efficiency analysis.
Gene and transcript abundance with Salmon, kallisto, RSEM.
Secondary-structure prediction with RNAfold, IPknot.
FASTA/FASTQ parsing, conversion, and indexing.
Transcription, translation, ORF finding, and motif search.
scRNA-seq clustering, annotation, trajectory, and integration.
miRNA, piRNA, and small-RNA quantification.
Visium, Slide-seq, and high-resolution tissue expression.
PDB parsing, AlphaFold, ESMFold, and structure analysis.
Metabolic flux balance, kinetic modelling, network analysis.
Immune-receptor repertoire profiling and clonal-family analysis.
Time-series and circadian expression analysis.
SNPs, indels, SVs with GATK, DeepVariant, Manta, Delly.
Snakemake, Nextflow, CWL, WDL pipeline scaffolding.
Ready-to-run analysis pipelines combining multiple skills.
Contribute to the right repository
BAAM content is split across the Biorouter app, the Biorouter Skills repository, the Biorouter Workflows repository, and separate extension repositories.
Biorouter app and landing site
BaranziniLab/biorouterUse the main Biorouter repository for application code, desktop UI, server code, documentation, and this landing website.
Biorouter GitHubBiorouter Skills
BaranziniLab/biorouter-skillsAdd, update, package, or discuss reusable skill bundles in the dedicated skills repository.
Skills GitHubBiorouter Workflows
Broccolito/biorouter-workflowsContribute portable YAML workflows, examples, and federated analysis workflows in the workflows repository.
Workflows GitHubExtension repositories
one repository per extensionEach extension is maintained in its own repository. Open the GitHub icon on that extension card to file issues, send PRs, or update releases.
Browse extension repos